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2024's Top 8 Trimethylglycine Supplements

Find out what to look for in a quality Trimethylglycine (TMG) supplement and what to watch out for

What is Trimethylglycine (TMG)?

Trimethylglycine (TMG) is a compound made up of the amino acid glycine along with three methyl groups. It’s produced in the body from the B vitamin choline and is also obtained from the diet.

Trimethylglycine is an osmolyte, meaning it has an affinity for water and promotes fluid balance in the cells. It allows our cells to be resilient to stress and guards them against premature death.

Natural Sources of Trimethylglycine (TMG)

  • Beetroot
  • Meat
  • Seafood  
  • Green Leafy Vegetables
  • Grains
  • Legumes

Benefits Of TMG

✔️ Encourages Methylation

Methylation is a biological process which is thought to be key to turning on genes which lead to good health and turning off genes which lead to bad health.

✔️ Supports Heart Health

Trimethylglycine is considered a heart-supportive nutrient because it lowers levels of the compound homocysteine, a blood marker of cardiovascular disease.

✔️ Balances Mood

By donating methyl groups, TMG improves the synthesis of a compound called s-adenosylmethionine (SAMe) that helps to regulate serotonin levels in the brain.

✔️ Boosts Athletic Performance

Research suggests that supplementing with TMG may improve endurance, increase strength, increase training volume, and increase exercise quality.

✔️ Regulates Blood Sugar

A 2016 study found that having higher levels of trimethylglycine – due to lifestyle changes – was associated with lower diabetes risk.

Before You Buy

Trimethylglycine is generally safe to take. However, research has shown it has the potential to increase levels of LDL cholesterol and total cholesterol.

If you struggle with high cholesterol or are taking cholesterol-lowering medication, speak to your doctor before taking trimethylglycine supplements.

2024's Top 8 Trimethylglycine Supplements

1. Quality 

All the products we recommend have been third party tested to ensure they meet our high standards of quality.

2. Cost 

Getting your hands on a high quality supplement doesn’t have to break the bank. While our top priority will always be quality, we understand that price factors into many people’s buying decisions.

3. Brand Reputation

To ensure that your buying experience is a pleasant one, we recommend only products from companies with strong reputations for providing quality customer service and prompt shipping.

OVERALL RATING

99%

Nutricost TMG is the #1 Rated TMG Supplement, as it is high quality and half the price of its competitors. Nutricost TMG features 750MG of Trimethylglycine per capsule, and 120 capsules per bottle. Click Here for Lowest Price

Uniquely, Nutricost is one of the few companies that control the full chain of manufacturing, from sourcing to manufacturing in an FDA-registered facility to warehousing and fulfillment, ensuring strict quality standards are met. Nutricost also offers exceptional customer support for all of its products.

Priced at $10, Nutricost TMG comes with 120 servings, which is just $0.08 per serving. With Nutricost, you can be assured that this product does NOT contain ANY extra ingredients, fillers, or preservatives.

Nutricost TMG comes with a 120-day, no-questions-asked, money-back guarantee – the best guarantee on the market!

  • 750mg of TMG Per Capsule
  • 120 Capsules Per Bottle
  • High Quality TMG (Trimethylglycine)
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Made in a GMP Compliant, FDA Registered Facility

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

OVERALL RATING

99%

Amazon Price: $27.96

  • Clean & Pure Powder. No Fillers.
  • Factory Sealed Foil Zip Pouch.
  • Lab Tested for Verification & Guaranteed Purity.

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

OVERALL RATING

89%

Amazon Price: $19.99

  • PURE TMG BETAINE ANHYDROUS TRIMETHYLGLYCINE
  • NO STEARATES OR RICE FILLERS.
  • 6 MONTHS SUPPLY
  • MADE IN THE USA
  • LOVE IT OR IT’S FREE! We offer a HASSLE-FREE, 100% MONEY BACK GUARANTEE.

 

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

OVERALL RATING

87%

Amazon Price: $9.99

  • Helps to Balance Homocysteine Levels
  • Aids Liver Function
  • Promotes Cardiovascular Health
  • 100% PURE
  • MADE IN USA

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

OVERALL RATING

83%

Amazon Price: $9.99

  • Supports healthy liver function
  • Supports detoxification
  • Supports normal homocysteine levels
  • Manufactured According to GMP

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

OVERALL RATING

80%

Amazon Price: $19.99

  • DERIVATIVE OF GLYCINE: Genex Trimethylglycine is derived from glycine, an essential amino acid. It provides a natural source of Trimethylglycine, also known as TMG. TMG has been researched for its ability to enhance liver function, support cellular reproduction, support heart health, and promote healthy homocysteine levels. Incorporating TMG supplements into your daily routine can help optimize your overall well-being.
  • 2 DOSAGE OPTIONS: Genex TMG Supplement is available in two convenient dosage strengths: 500mg and 1000mg. This ensures that individuals have the flexibility to choose the dosage that aligns with their specific needs and preferences. Each bottle of Genex TMG provides a 30-day supply, allowing for consistent and convenient usage throughout the month. With these two dosage options, you can easily tailor your TMG intake to suit your personal requirements and goals.
  • HIGH-QUALITY MANUFACTURING: Genex Formulas takes pride in its commitment to producing premium supplements. The TMG supplement is manufactured in a state-of-the-art facility that is GMP (Good Manufacturing Practice) certified. This certification guarantees that the manufacturing process adheres to strict quality control measures and industry standards. By choosing Genex TMG, you can trust in the product's exceptional quality and efficacy, backed by meticulous manufacturing practices.
  • COMPREHENSIVE DIETARY COMPATIBILITY: Our TMG supplements are formulated to accommodate a wide range of dietary preferences and restrictions. Genex TMG is completely non-GMO, vegan-friendly and free from gluten, making it suitable for individuals following plant-based or gluten-free diets. The product has also undergone rigorous lab testing, ensuring its purity and safety. It contains no artificial flavors or colors, providing a clean and natural supplement option.
  • ALLERGEN-FREE FORMULATION: Our Trimethylglycine is designed to be inclusive and allergen-friendly. It does not contain milk, eggs, fish, soy, or yeast, making it an excellent choice for individuals with common allergen sensitivities or dietary restrictions. With Genex TMG, you can enjoy the benefits of this remarkable liver supplement without worrying about potential allergens or compromising your dietary needs.

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

OVERALL RATING

78%

Amazon Price: $40.68

  • Helps to Balance Homocysteine Levels
  • Aids Liver Function
  • Promotes Cardiovascular Health
  • 100% PURE
  • MADE IN USA

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

OVERALL RATING

77%

Amazon Price: $26.29

  • More than 40 years of experience formulating original, leading-edge supplements
  • Hypoallergenic products and natural ingredients
  • Third-party testing with certified independent analytical laboratories.
  • Products meet or exceed cGMP requirements established by the FDA.

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

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