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2025's Top 10 R-Alpha Lipoic Acid
Find out what to look for in a quality R-Alpha Lipoic Acid and what to watch out for
What is R-Alpha Lipoic Acid?
R-Alpha Lipoic Acid, or R-ALA, is a naturally occurring compound and cofactor that plays a vital role in energy metabolism. It is also a potent antioxidant with the ability to protect cells from oxidative damage caused by free radicals. Unlike other antioxidants, R-ALA is both water and fat-soluble, making it able to work in all parts of the body. R-ALA is synthesized in small amounts within the body, but it can also be obtained through food or as a supplement.
Benefits of R-Alpha Lipoic Acid
1. Anti-Aging Effects
R-Alpha Lipoic Acid is known for its anti-aging properties. It protects your skin from free radicals that cause wrinkles and fine lines. It also helps to stimulate collagen production, leading to a more youthful look. ALA's antioxidant properties help in reducing, preventing and improving brain aging, protecting you against cognitive decline, neuroinflammation and memory loss.
2. Anti-Inflammatory Benefits
Inflammation is a natural process in the body's response to infection or injury. However, chronic inflammation is linked to many health conditions, including obesity, heart disease, and cancer. R-Alpha Lipoic Acid has anti-inflammatory properties, reducing the risk of chronic inflammation, leading to improved overall health. ALA supplementation has also been linked to reducing pain and discomfort associated with conditions such as osteoarthritis and rheumatoid arthritis.
3. Supports Diabetic Health
R-Alpha Lipoic Acid has been found to be beneficial in diabetes by improving insulin sensitivity and reducing blood sugar levels. ALA helps cells to better use insulin, which helps to maintain glucose levels. The supplement also benefits nerve health, reducing the risk of nerve damage in people with diabetes. Moreover, ALA has been reported to help reduce peripheral neuropathy, a common complication of diabetes that leads to numbness and tingling in hands and feet.
4. Cardiovascular Health
R-Alpha Lipoic Acid protects the heart by reducing oxidative stress. It also reduces inflammation in the cardiovascular system, reducing the risk of heart disease. ALA also helps to decrease blood pressure levels, making it an excellent supplement for people at risk of high blood pressure.
5. Liver Health
R-Alpha Lipoic Acid plays an essential role in liver health by detoxifying the liver. It also helps in breaking down toxins and supporting the liver's functioning, ultimately reducing the risk of liver diseases. Research suggests that ALA helps in reducing liver inflammation, which can lead to certain liver conditions such as fatty liver disease, hepatitis, and cirrhosis.
Potential Side Effects
1. Low Blood Sugar:
One of the most notable side effects of R-Alpha Lipoic Acid is its potential for causing low blood sugar. In some cases, R-ALA supplements may cause blood sugar levels to drop considerably. People with diabetes who use insulin should take extra care when using ALA, as their hypoglycemia signals might be masked while taking this supplement. It is essential to speak to a healthcare provider before trying this supplement, particularly if you are taking insulin or other blood sugar-lowering medications.
2. Skin Rashes:
Individuals who have sensitive skin or certain allergies may experience skin rashes. The reason behind this is the supplement's property to boost blood circulation and dilate blood vessels, which can cause rashes. If you experience rashes, discontinue use, and consult your doctor.
2023's Top 10 R-Alpha Lipoic Acid
1. Quality
All the products we recommend have been third party tested to ensure they meet our high standards of quality.
2. Cost
Getting your hands on a high quality supplement doesn’t have to break the bank. While our top priority will always be quality, we understand that price factors into many people’s buying decisions.
3. Brand Reputation
To ensure that your buying experience is a pleasant one, we recommend only products from companies with strong reputations for providing quality customer service and prompt shipping.
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- 100mg of R-Alpha Lipoic Acid (R-ALA) Per Capsule
- 240 "Veggie Caps" for 240 Serving Per Bottle (1 Serving, Just 1 Capsule)
- Just the R-ALA Version of Alpha Lipoic Acid
- Non-GMO, Vegetarian Friendly, Gluten Free, 3rd Party Tested
- Made in a GMP Compliant, FDA Registered Facility
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- WHY OUR LIPOIC ACID IS “SUPER” - Most supplements use a 50/50 ratio of the active “R” form of lipoic acid, which means it’s challenging for your body to absorb it fully. But based on numerous studies, we’ve developed a formula that includes a highly bioavailable form of lipoic acid. The biologically active “R” form reaches higher blood concentration sooner, giving your body more of this nutrient to use, and more time to use it so that you get maximum benefits of this powerful antioxidant.
- Product Note: Exposure to heat or sunlight may lead to melting/damage of product. Hence customers are expected to be available during the product delivery
- KEEP THE ENERGY FLOWING - The highly bioavailable “R” form of lipoic acid in our formula has remarkable antioxidant properties. It helps protect your mitochondria from oxidative stress caused by free radicals, promoting healthy mitochondrial function and encouraging youthful cellular energy.
- HIGH BIOAVAILABILITY, RAPID INTAKE - Bioavailability is the time it takes for an ingested supplement to reach the bloodstream—as well as how much of it gets absorbed. The more bioavailable a supplement is, the more beneficial it is. Our innovative formula has up to 30 times the bioavailable levels of standard R-lipoic formulas. It’s designed to ensure rapid uptake from the plasma into the tissues—all in an easy-to-swallow capsule.
- INGREDIENTS MATTER - Sourced using only the finest raw ingredients with the purity and potency your body deserves; This product is certified non-GMO and gluten-free; Manufactured in the USA and a Certificate of Analysis is available
- LIVE YOUR HEALTHIEST LIFE - We believe the answers to a healthier, richer life are within reach and that rigorous scientific research is the path to get us there; Formulations are created using the exact ingredients and dosages
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- STABILIZED R-LIPOIC ACID: Enhanced with Biotin optimizer for additional daily support
- OPTIMAL FORM: Quick release capsules feature 300 mg of Stabilized R-Lipoic Acid per serving
- ROOTED IN WELLNESS: Carlyle provides premium, honest supplements in your pursuit to healthy living
- CARLYLE MANUFACTURERS: Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
- NATURALLY FREE OF: Gluten, Wheat, Yeast, Lactose, Soy, Artificial Flavor, Preservatives and Non-GMO
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- POWERFUL ANTIOXIDANT: Alpha Lipoic Acid(ALA) the universal anti-oxidant is vital to your health, but sometimes your body doesn't have enough. It exists as R-ALA and S-ALA. R-ALA is the only version found in nature and the version your body needs. S-ALA is unnatural, and a synthetic byproduct created during the production process.
- STABILIZED & HIGH POTENCY: R-ALA the High Potency supplement when not formulated correctly can be useless. Once R-ALA is connected to Sodium(Na), it is STABILIZED, which prevents the R-ALA from becoming unstable and prevent it from polymerizing and becoming inactive.
- HIGH ABSORPTION: Stabilized R-Alpha Lipoic Acid has been shown to have 40x more absorption to help produce desirable biological actions and bind to key enzymes.
- CONTAINS NO S-ALPHA LIPOIC ACID: Typical ALA products are a combination of both R and S versions of ALA, meaning 50% of the product is spent on an ineffective and hindering product.
- SUPPLEMENT FACTS BOXES: With so many Alpha Lipoic Acid to choose from, always confirm the Supplement Facts box on the label states "STABILIZED (Na) R-Alpha Lipoic Acid" and that it does not list “S”-Alpha Lipoic Acid.
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- DOCTOR’S BEST STABILIZED R-LIPOIC ACID CONTAINS BIOENHANCED NA-RALA - the sodium salt of R-Lipoic acid (RLA). BioEnhanced Na-RALA is in its natural and stabilized form of RLA that won’t degrade at high temperatures and is more bioavailable and biologically active. Lipoic acid (LA) plays an important role in glucose metabolism and energy production. LA is both fat and water soluble. D-Biotin is an integral part of enzyme activity necessary for the breakdown and conversion of fatty acids and carbohydrates into energy
- POWERFUL ANTIOXIDANT – Lipoic acid is a potent antioxidant that supports mitochondrial function, helps protect against oxidative stress and maintains cellular energy. Supports nerve health, glucose metabolism and cardiovascular health.
- CELLULAR ENERGY - R-lipoic acid is made by the body in our mitochondria, the cells that provide energy. Protecting mitochondria from free radicals, R-Lipoic Acid supports energy at the cellular level.
- BETTER ABSORPTION - R-Lipoic Acids includes the active “R” form of lipoic acid, stable and easier for the body to absorb. Improved stability from this formula is the cause for better absorption and bioavailability.
- During the summer months products may arrive warm but Amazon stores and ships products in accordance with manufacturers' recommendations, when provided.
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- Cellular Energy Production, Glucose & Lipid Metabolism and Antioxidant Support Supplement: Contains one 60 count bottle of Jarrow Formulas R-Alpha Lipoic Acid veggie capsules for a 60-day supply
- Dietary supplement with 100 mg of R-Alpha Lipoic Acid (RALA), a naturally occurring form of Alpha Lipoic Acid to support cellular energy production, support glucose and lipid metabolism, and as an antioxidant helps to minimize oxidative stress
- Each serving includes 150 mcg of Biotin to prevent Biotin deficiency associated with long-term Alpha Lipoic Acid use
- Suggested Use: Adults, take one capsule once a day or as directed by your qualified healthcare professional
- These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- ENHANCED ABSORPTION - GeroNova Bio-Enhanced R-Lipoic Acid is the most absorbable form of lipoic acid as it's the exact type the body requires, making it 40x more bioavailable and more potent than typical Lipoic Acid.
- ANTIOXIDANT PROTECTION - As a powerful antioxidant, Bio-Enhanced R-Lipoic Acid protects against oxidative stress, rejuvenating the body's cells, and keeping you strong and healthy.
- ENERGY PRODUCTION AND METABOLIC SUPPORT - Our mitochondria produce the energy that powers our cells. However, they lose optimal function over time. Lipoic Acid helps increase energy conversion and maintain cellular health.
- QUALITY INGREDIENTS - Made in a cGMP and a USDA organic-certified facility to meet stringent US Pharmacopeia standards for quality, purity, potency, and disintegration.
- PURITY - This product is gluten-free, dairy-free, non-GMO, and does not contain wheat, corn, yeast, soy, egg, artificial colors, artificial sweeteners, or artificial flavors.
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- CLINICAL DOSAGE: Each serving contains a potent 600mg dose of R Alpha Lipoic Acid, a powerful antioxidant that helps neutralize free radicals, reducing oxidative stress and supporting healthy cellular function. Each bottle holds 60 R Alpha Lipoic Acid 600mg Capsules.
- WITH BIOTIN: Each serving also contains 300mcg Biotin to prevent Biotin Deficiency that often occurs with continued use of R Alpha Lipoic Acid.
- POWERFUL ANTIOXIDANT SUPPORT: R-Alpha Lipoic Acid is renowned for its potent antioxidant properties, defending against oxidative damage and promoting a healthy inflammatory response, supporting the overall health of your cells.
- CELLULAR ENERGY AND METABOLISM SUPPORT: R Alpha Lipoic Acid plays a vital role in cellular energy production, converting glucose into usable energy. By supporting optimal mitochondrial function, it helps maintain energy levels throughout the day, promoting vitality and well-being.
- 3RD PARTY LAB TESTED IN THE USA: We have our own GMP and FDA registered Food-Grade facility in the USA. All our products are 3rd-Party tested to guarantee purity. Satisfaction Guaranteed: At Nutri we guarantee almost everything Forever. Please contact us for any refund or return issue as Amazon "does not allow" returns on supplements, but we do.
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- Superior quality nutrition at the best value
- Designed to support your healthy lifestyle goals
- Devoted to Purity, Potency and Safety!
- Non-GMO and Gluten Free
- Laboratory Tested, using Trusted Ingredients
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.
- Active Form: The active isomer form of R-Lipoic Acid
- Antioxidant: A versatile antioxidant in both water- and fat-soluble tissues*
- Liver/Eyes: Promotes liver health and eye health*
- Brain & Nerves: Supports healthy nerve function and brain function*
- Trusted: Thorne is chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of U.S. Olympic Teams
*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.