2021's 10 Best Trimethylglycine (TMG)
TOP SUPPLEMENTS

Best Trimethylglycine (TMG)

Trimethylglycine – also known as (betaine anhyrous) – is a compound made up of the amino acid glycine along with three methyl groups. It’s produced in the body from the B vitamin choline and is also obtained from the diet. Trimethylglycine is predominantly found in its namesake food, beetroot, but also occurs in meat, seafood, green leafy vegetables, grains and legumes. However, taking a supplemental form makes it easy to boost your levels.

Trimethylglycine is an osmolyte, meaning it has an affinity for water and promotes fluid balance in the cells. It allows our cells to be resilient to stress and guards them against premature death.

Here are more impressive health benefits of Trimethylglycine.

Trimethylglycine Benefits

Encourages Methylation

One of Trimethylglycine’s main jobs is as a methyl donor, and many of its benefits are attributed to this.

Each Trimethylglycine molecule contains three methyl groups – three hydrogen molecules bound to a carbon molecule – which are essential for a metabolic process called methylation. Trimethylglycine donates methyl groups to form other compounds in the body that reduce free radical damage and support cardiovascular, neurological, reproductive and liver health.

Supports Heart Health

Trimethylglycine is considered a heart-supportive nutrient because it lowers levels of the compound homocysteine, a blood marker of cardiovascular disease. It does this by methylating homocysteine back into the amino acid methionine.

Homocysteine is produced by the body, but when levels get too high it can cause blood vessel damage as well as atherosclerosis (hardening of the arteries) – both precursors of heart disease.

A 2013 meta-analysis found that taking 4g of Trimethylglycine supplementation daily significantly decreased plasma homocysteine levels.

Balances Mood

Trimethylglycine may be useful for those suffering from low mood and anxiety. By donating methyl groups, it improves the synthesis of a compound called s-adenosylmethionine (SAMe) that helps to regulate serotonin levels in the brain. This means more of the “happy hormone”!

A 2015 study on adults with mild-to-moderate depression found that taking trimethylglycine – along with SAMe – for 3 months reduced feelings of anxiety, agitation, helplessness and worthlessness. The results were better for those who took the combination compared to those who only took SAMe.

Boosts Athletic Performance and Muscle Growth

Trimethylglycine is becoming a popular addition to pre-workout supplements and protein shakes. It supports performance and boosts gains at the gym!

Research backs this up. Studies show supplementing with trimethylglycine may provide the following benefits:

  • Improved endurance
  • Increased strength and power
  • Increased training volume
  • Greater quality and number of exercise repetitions

There’s no doubt being able to perform more repetitions for longer will lead to greater muscle growth. However, a 2013 study found that 1.25g of trimethylglycine daily for 2 weeks also increased markers of muscle protein synthesis – like human growth hormone – after a workout.

Regulates Blood Sugar Levels

Trimethylglycine is an exciting supplement for treating insulin resistance and blood sugar imbalances. A 2016 study found that having higher levels of trimethylglycine – due to lifestyle changes – was associated with lower diabetes risk.

Studies on animal subjects have found that trimethylglycine can improve insulin sensitivity and glucose tolerance. However, more clinical studies are needed.

Trimethylglycine Considerations

Trimethylglycine is generally safe to take. However, research has shown it has the potential to increase levels of LDL cholesterol and total cholesterol. If you struggle with high cholesterol or are a taking cholesterol-lowering medication, speak to your doctor before taking trimethylglycine supplements.


2021's 10 Best Trimethylglycine (TMG)
TOP SUPPLEMENTS

Our list of the top 10 alpha lipoic acid supplements is organized to reflect what you most value in your supplements. First and foremost is quality. All ten of these top ten supplements meet high standards of quality and come from brands with a proven record in excellence and purity. Another important factor in deciding the top ten was cost. You don’t have to pay through the nose to get a high quality supplement. In addition, all the companies represented on our top ten list have stellar records with customer service and prompt shipping to ensure that your supplement experience is enjoyable from the first click to your final dose.

Nutricost Trimethylglycine Capsules are our #1 Rated Trimethylglycine Supplement, as it is high quality and half the price of its competitors. Nutricost Trimethylglycine features 75000 mg of Trimethylglycine in each serving. Click Here for Lowest Price

Uniquely, Nutricost is one of the few companies that control the full chain of manufacturing, from sourcing to manufacturing in an FDA-registered facility to warehousing and fulfillment, ensuring strict quality standards are met. Nutricost also offers exceptional customer support for all of its products.

Priced at $10, Nutricost Trimethylglycine comes with 120 capsules, which is just $0.08 each!. With Nutricost, you can be assured that this product does NOT contain ANY extra ingredients, fillers, or preservatives.

Nutricost Trimethylglycine comes with a 120-day, no-questions-asked, money-back guarantee – the best guarantee on the market!

  • Our #1 Trimethylglycine!
  • Amazon's Choice
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  • Potent 750 mg Per Serving
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Made in a GMP Compliant, FDA Registered Facility
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*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Clean & Pure Powder. No Fillers.
  • Factory Sealed Foil Zip Pouch.
  • Lab Tested for Verification & Guaranteed Purity.
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*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Pure betaine anhydrous (Trimethylglycine - TMG)
  • Unflavored
  • Direct from our Factory
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*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • PURE TMG BETAINE ANHYDROUS TRIMETHYLGLYCINE
  • NO STEARATES OR RICE FILLERS.
  • 6 MONTHS SUPPLY
  • MADE IN THE USA
  • LOVE IT OR IT’S FREE! We offer a HASSLE-FREE, 100% MONEY BACK GUARANTEE.
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*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Helps to Balance Homocysteine Levels
  • Aids Liver Function
  • Promotes Cardiovascular Health
  • 100% PURE
  • MADE IN USA:
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*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Supports healthy liver function
  • Supports detoxification
  • Supports normal homocysteine levels
  • Manufactured According to GMP
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*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Vegetarian
  • Non-GMO
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*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Helps to Balance Homocysteine Levels
  • Aids Liver Function
  • Promotes Cardiovascular Health
  • 100% PURE
  • MADE IN USA:
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

Nutricost Betaine Anhydrous powder is our #1 Rated Betaine Anhydrous Supplement, as it is high quality and half the price of its competitors. Nutricost Betaine Anhydrous features 1500 mg of Beta Glucan in each serving. Click Here for Lowest Price

Uniquely, Nutricost is one of the few companies that control the full chain of manufacturing, from sourcing to manufacturing in an FDA-registered facility to warehousing and fulfillment, ensuring strict quality standards are met. Nutricost also offers exceptional customer support for all of its products.

Priced under $15, Nutricost Betaine Anhydrous comes with 330 capsules, which is just $0.04 per serving!. With Nutricost, you can be assured that this product does NOT contain ANY extra ingredients, fillers, or preservatives.

Nutricost Betaine Anhydrous comes with a 120-day, no-questions-asked, money-back guarantee – the best guarantee on the market!

  • Our #1 Betaine Anhydrous!
  • Amazon's Choice
  • Under a Nickel per Serving!
  • Potent 1500 mg Per Serving
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Made in a GMP Compliant, FDA Registered Facility
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Trimethylglycine (TMG) is a compound found in beet root and other plants and animal foods.
  • Suitable for vegetarians. Contains no yeast, dairy, egg, gluten, corn, soy or wheat. Contains no sugar, starch, salt,
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*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.