2021's 10 Best Methylfolate
TOP SUPPLEMENTS

Best Methylfolate

You’ve likely heard of folic acid or vitamin B9, the nutrient essential at every stage of life. It enables cell growth and maintains and repairs DNA. However, folic acid must first be broken down and “activated” by the liver before it can be used.

Luckily, methyl folate is the active form of folic acid – also known as methyltetrahydrofolate (MTHF) – that’s easily usable by the human body and can cross the blood-brain barrier.

The body isn’t able to produce folate by itself – it needs to come from diet or supplements. Foods high in folate include:

  • Green leafy vegetables
  • Asparagus
  • Broccoli
  • Avocado
  • Bananas
  • Citrus fruits
  • Lemons
  • Organ meats
  • Eggs
  • Grains
  • Legumes
  • Nuts

Methylfolate supplements are also a great addition to your diet.

Signs of Low Folate

Research suggests more than 40% of people – some ethnic groups being more at risk – may have a genetic mutation that impairs the conversation of folic acid into active methylfolate. This explains why many people have low folate levels and symptoms like fatigue, low iron, low mood, heart problems and increased risk of birth defects.

Others factors that increase the risk of low folate levels include:

  • Pregnancy
  • Restrictive diets
  • Digestive disorders
  • Poor kidney function
  • Alcohol
  • Smoking

Here are some of the health benefits of methylfolate.

Benefits of Methylfolate

Iron Levels and Energy

Folate is essential for the production of red blood cells that contain a protein called hemoglobin. Hemoglobin carries iron and oxygen around the body, so a low red blood cell count reduces our oxygen capacity, resulting in weakness and fatigue.

Healthy Pregnancy

Its role in cell development makes folate a must-have nutrient for pregnant women and those wanting to conceive.

The body’s folate demands increase during pregnancy as it’s essential for proper fetal development. Healthy folate levels have also been linked to a reduced risk for premature birth. This is why folic acid is found in all prenatal supplements.

A folate deficiency in pregnancy is very risky for mom and baby, particularly when it comes to neural tube defects – poor development of the brain, spinal cord and spine.

In addition to a whole food diet, active methylfolate is the safest supplement to take during pregnancy because it won’t build up in the bloodstream.

Heart Health

Methylfolate is a key nutrient for supporting heart health. Folate – especially when used in conjunction with vitamin B6 and B12 – helps to methylate homocysteine into the non-toxic amino acid methionine. This process normalizes levels of an amino acid called homocysteine, high levels of which are linked to inflammation, blood vessel damage, hardening of the arteries and increased heart disease risk.

Mood

Low levels of methylfolate have been noted in those struggling with poor moods.

By converting homocysteine into methionine, folate assists in a process that boosts levels of the amino acid s-adenosylmethionine (SAM-e). This is necessary for the production of our brains “feel good” chemicals known as neurotransmitters – like serotonin, norepinephrine and dopamine.

A 2016 study looked at the impact of folate on people with mood disorders who were unresponsive to conventional medication. In addition to selective serotonin reuptake inhibitor (SSRI) medication, they were given 15mg of methylfolate daily for one year. The results found that many of the subjects who also took methylfolate achieved symptom remission or had a significant improvement in mood.


2021's 10 Best Methylfolate
TOP SUPPLEMENTS

Our list of the top 10 methyl folate supplements is organized to reflect what you most value in your supplements. First and foremost is quality. All ten of these top ten supplements meet high standards of quality and come from brands with a proven record in excellence and purity. Another important factor in deciding the top ten was cost. You don’t have to pay through the nose to get a high quality supplement. In addition, all the companies represented on our top ten list have stellar records with customer service and prompt shipping to ensure that your supplement experience is enjoyable from the first click to your final dose.

Nutricost Methylfolate Capsules are our #1 Rated Methyl Folate Supplement, as it is high quality and half the price of its competitors. Nutricost Methylfolate Capsules feature 1000 mcg of Methylfolate in each serving. Click Here for Lowest Price

Uniquely, Nutricost is one of the few companies that control the full chain of manufacturing, from sourcing to manufacturing in an FDA-registered facility to warehousing and fulfillment, ensuring strict quality standards are met. Nutricost also offers exceptional customer support for all of its products.

Priced under $13, Nutricost Methylfolate Capsules come with 120 capsules, which is just $0.11 each!. With Nutricost, you can be assured that this product does NOT contain ANY extra ingredients, fillers, or preservatives.

Nutricost Methylfolate comes with a 120-day, no-questions-asked, money-back guarantee – the best guarantee on the market!

  • Our #1 Methylfolate!
  • Amazon's Choice
  • Only $0.11 per Serving!
  • Potent 1000 mcg Per Serving
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Made in a GMP Compliant, FDA Registered Facility
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Gluten Free, Non-GMO; Free Of Wheat, Yeast, Milk, Lactose, Soy, Artificial Color, Artificial Flavor
  • Each L-Methylfolate (5-MTHF) capsule provides you with 15 mg of this bioavailable form of folic acid
  • Folate, also referred to as Folic Acid, is a fully active B complex vitamin
  • This B-complex vitamin supports nervous system health and is involved in neurotransmitter synthesis
  • Non-GMO, Gluten Free, 3rd Party Tested
  • Helps maintain levels of homocysteine already within a normal range
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • METHYLFOLATE TABLETS
  • ABSORPTION
  • ENHANCED MOOD
  • CHEWABLE TABLETS
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • 4th generation folic acid technology
  • The more stable, more bioavailable form of folate
  • No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts
  • Suitable for Vegetarians
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • THE LEADER IN FASTER, ACTIVE FOLATE
  • PROFESSIONAL STRENGTH
  • BRAIN & MOOD SUPPORT
  • PROMOTES CARDIOVASCULAR & NERVE HEALTH
  • NO FILLERS
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Contains 1000 mcg of the methylated form of Folate
  • Metabolically Active Folate Healthy Neurological Development
  • 90 Chewable Tablets, 90 Servings
  • Soy-Free, Gluten-Free, Non-GMO, Kosher Certified, Dairy-Free, Vegan
  • Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans. Also free of yeast, gluten, barley, rice and sodium.
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • ACTIVATED FORM OF FOLATE
  • SUPPORTS CARDIOVASCULAR HEALTH
  • PROMOTES HEALTHY NERVOUS SYSTEM
  • QUALITY MADE IN THE USA
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Contains 1000 mcg of the methylated form of Folate
  • Metabolically Active Folate Healthy Neurological Development
  • 90 Chewable Tablets, 90 Servings
  • Soy-Free, Gluten-Free, Non-GMO, Kosher Certified, Dairy-Free, Vegan
  • Free of milk, egg, fish, crustacean shellfish, tree nuts, peanuts, wheat and soybeans. Also free of yeast, gluten, barley, rice and sodium.
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • ESSENTIAL NUTRIENT
  • CONVENIENT FORM
  • EXPERTLY CRAFTED
  • SUPERIOR BIOAVAILABLITY
  • Laboratory Tested, Trusted Ingredients, Superior Quality, 100% Guaranteed!
  • NATURALLY FREE OF: Gluten, Wheat, Yeast, Milk, Lactose, Soy, Artificial Color & Flavoring & NON-GMO
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.

  • Lab tested and most powerful Methylfolate supplying essential support for DNA and neurotransmitter synthesis along with amino acid metabolism.
  • Developed as most optimally absorbed and bioavailable 5-MTHF
  • Delivering key supplementation for brain, heart and nerve function, as well as support for women who are pregnant and overall health
  • Suitable for people who are diagnosed with MTHFR mutation
  • To ensure purity and safety, our products are manufactured in a fully GMP-certified facility
  • All Made in USA.
CLICK FOR LOWEST PRICE

*Individual Results May Vary - Ratings are based on Society Health Ranking System and do not necessarily reflect typical results from the use of these products. We encourage consumers to research by visiting each product's website for more information.